Explore the Future of Biomanufacturing
Welcome to my blog! I'm James, a strategic advisor and coach with over 20 years of experience in biotech and executive leadership. I've built high-performing teams and led groundbreaking research in stem cell metabolism, regenerative medicine, and cultured meat. As a passionate advocate for biomanufacturing's world-changing potential, I'm excited to share my knowledge and ideas with you.
What You’ll Discover Here
🔬 Latest Innovations: Explore cutting-edge advancements in biomanufacturing, cultivated meat, and cellular agriculture.
🚀 Founder's Corner: Access valuable tools and insights developed for my coaching program, tailored specifically for technical founders.
🎙️ Industry Voices: Every two weeks, enjoy an in-depth interview with a founder, investor, or operator in the biomanufacturing space.

“Amateurs discuss tactics, professionals discuss logistics.”
While dialing in your scientific strategy is critical, don’t neglect your supply chain strategy—because as Sun Tzu said, “The line between disorder and order lies in logistics.”

🚀 Great news for biomanufacturing in Australia!
Australia excels at producing world-class scientific research, but we’ve historically struggled to translate those discoveries into commercial outcomes. The AEA aims to change that, providing crucial support for academic researchers working in the seven priority areas of the National Reconstruction Fund.

The Changing Landscape of Non-Clinical Biomanufacturing (update for 2025) 🚀
I’ve mapped out an end-to-end value chain highlighting the B2B companies shaping the non-clinical biomanufacturing space. I shared a version of this map almost 12 months ago, and since then the number of companies has exploded (with a few that have pivoted and a few that haven't been successful).

The Sweet Revolution: How Feedstocks Will Shape the Future of Biomanufacturing
Biomanufacturing is reshaping industries—from food and textiles to specialty chemicals and biofuels—by harnessing biology to create high-value products. This field spans technologies like cell cultivation, fermentation, enzymatic processes, molecular farming, and synthetic biology.
While innovations like cultivated meat and precision-fermented dairy often steal the spotlight, one critical factor is often overlooked: feedstocks. As the industry scales, the demand for sustainable, cost-effective raw materials to power these processes is skyrocketing.

🚀 Five Breakthrough Technologies Driving Down COGS in Fermentation-Based Biomanufacturing
Here are five companies developing game-changing technologies that could help make fermentation-based production more cost-effective in 2025 (and beyond)

🎙️ A Green Genie to Grant Your Biomass Yield Wishes
This week, I had the pleasure of chatting with Nick Hazell, founder and CEO of Algenie, and previously the founder and CEO of plant-based food company v2food.

🚀 5 Breakthrough Advances in Upstream Bioprocessing That Are Reshaping Biomanufacturing 🚀
For non-clinical biomanufacturers, the priority is clear: drive up yield, drive down costs, and scale effectively. Here are five cutting-edge technologies I’ve come across in the last 12–18 months that are set to make waves:

🎙️ How an Octopus can Accelerate your Bioprocess - An interview with Cristofer Rybner of Reocto
For biomanufacturing to have the global impact we’re all hoping for, many things will need to change. Biomanufactured products like food and textiles, while starting in the luxury space, must eventually come down in price to become widely accessible. This will require changes to the underlying technologies. One critical piece of infrastructure is the bioreactor—where cells or organisms are grown at a massive scale 🌱.

🎙️Protein from Air? - An Interview with David McLellan from Jooules
Gas fermentation feeds bacteria with CO₂, hydrogen, and nitrogen, allowing them to grow rapidly, doubling in under an hour. This produces a “complete” protein rich in essential amino acids, making it a highly attractive ingredient. 🍽️

🍖 Waste Valorisation and "everything but the oink"
Beyond biotech innovations and hybrid product development, there’s another compelling path to profitability for cultured meat: waste stream valorization. ♻️ In traditional animal agriculture, every part of the animal finds a use—hence the saying, “everything but the oink.”

🚀 The Biomanufacturing Revolution: Australia's Golden Opportunity 🏭🌲
Biomanufacturing is set to revolutionize global industries, from food and textiles to cosmetics, biofuels, and industrial chemicals. McKinsey reports that up to 60% of consumer goods could have bio-based alternatives, while Boston Consulting Group estimates a staggering $30 trillion in economic potential.
🚀 The Biomanufacturing Revolution is here!
🚀For those following my journey, you know I'm passionate about the bio-based manufacturing sector. But what exactly is biomanufacturing, and why should you care?

🚀 To vertically integrate or not? 🏭
As bio-based manufacturing expands, companies must decide whether to vertically integrate or partner with a CDMO. So many variables must be considered when making this decision, not least of which is maintenance and upkeep costs.

🎙️ Values before mission?
As part of my weekly interview series, I had the opportunity to sit down with Mohammad from Bright Biotech to learn more about his journey as a founder and the challenges he has faced along the way. 🚀

🚀 Are You Pulling on All Three Biomanufacturing Optimisation Levers?
As more and more biomanufacturing companies seek to bring their products to market, pulling on all three optimisation levers—cell line development, media formulation, and bioprocess optimization—is critical for success.

🎙️ Schrödinger’s Egg - Here, but Not (from) Here 🥔
Founded in 2022, and funded by several VC’s (led by FoodLabs) PoLoPo is now growing ovalbumin-loaded potatoes in growth rooms in Israel. Ovalbumin is their first product—a protein used in a surprisingly large percentage of food products—but their vision extends much further. They plan to develop the potato as a manufacturing platform for dozens (eventually hundreds) of ingredients. Turning the humble potato into one of the worlds most advanced manufacturing facilities. 🏭

🚀A New Cell Line Development Database for Biomanufacturing 🔬📊
Today, I'm excited to share the third of these databases 📚, focusing on commercial cell lines and companies offering cell line development (CLD) services. I’ve mentioned before that I am bullish on the opportunity that exists within the cell-line and CLD spaces, and I remain strongly committed to this view.

🚀 Welcome to the (Bio)Revolution
I thought I'd share the five technologies I’m most excited by, in the biomanufacturing space. Keeping in mind that that over 60% of the physical inputs to the global economy could be produced by biomanufacturing, these are some of the technologies that will help drive the next phase of the biorevolution

🚀 Leveraging B2B Opportunities to Enhance Your Biomanufacturing Process
To assist those who are developing products using biomanufacturing, I have started a database of companies that can help through the provision of recombinant proteins, supplements, complete media formulations, or via media design and/or optimization strategies.

🚀Innovating Bioprocess Design: A New Database Resource
Given my strong personal interest in this space, I have started tracking as many companies as I can who are building innovative hardware or software solutions in the biomanufacturing space. If you are using biology to create incredible products, check out this brand-new bioprocessing database on my website now.