Explore the Future of Biomanufacturing

Welcome to my blog! I'm James, a strategic advisor and coach with over 20 years of experience in biotech and executive leadership. I've built high-performing teams and led groundbreaking research in stem cell metabolism, regenerative medicine, and cultured meat. As a passionate advocate for biomanufacturing's world-changing potential, I'm excited to share my knowledge and ideas with you.

What You’ll Discover Here

🔬 Latest Innovations: Explore cutting-edge advancements in biomanufacturing, cultivated meat, and cellular agriculture.
🚀 Founder's Corner: Access valuable tools and insights developed for my coaching program, tailored specifically for technical founders.
🎙️ Industry Voices: Every two weeks, enjoy an in-depth interview with a founder, investor, or operator in the biomanufacturing space.

The Changing Landscape of Non-Clinical Biomanufacturing (update for 2025) 🚀

The Changing Landscape of Non-Clinical Biomanufacturing (update for 2025) 🚀

I’ve mapped out an end-to-end value chain highlighting the B2B companies shaping the non-clinical biomanufacturing space. I shared a version of this map almost 12 months ago, and since then the number of companies has exploded (with a few that have pivoted and a few that haven't been successful).

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The Sweet Revolution: How Feedstocks Will Shape the Future of Biomanufacturing
Advances in Biomanufacturing James Ryall Advances in Biomanufacturing James Ryall

The Sweet Revolution: How Feedstocks Will Shape the Future of Biomanufacturing

Biomanufacturing is reshaping industries—from food and textiles to specialty chemicals and biofuels—by harnessing biology to create high-value products. This field spans technologies like cell cultivation, fermentation, enzymatic processes, molecular farming, and synthetic biology.

While innovations like cultivated meat and precision-fermented dairy often steal the spotlight, one critical factor is often overlooked: feedstocks. As the industry scales, the demand for sustainable, cost-effective raw materials to power these processes is skyrocketing.

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🎙️ How an Octopus can Accelerate your Bioprocess - An interview with Cristofer Rybner of Reocto

🎙️ How an Octopus can Accelerate your Bioprocess - An interview with Cristofer Rybner of Reocto

For biomanufacturing to have the global impact we’re all hoping for, many things will need to change. Biomanufactured products like food and textiles, while starting in the luxury space, must eventually come down in price to become widely accessible. This will require changes to the underlying technologies. One critical piece of infrastructure is the bioreactor—where cells or organisms are grown at a massive scale 🌱.

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🎙️ Schrödinger’s Egg - Here, but Not (from) Here 🥔

🎙️ Schrödinger’s Egg - Here, but Not (from) Here 🥔

Founded in 2022, and funded by several VC’s (led by FoodLabs) PoLoPo is now growing ovalbumin-loaded potatoes in growth rooms in Israel. Ovalbumin is their first product—a protein used in a surprisingly large percentage of food products—but their vision extends much further. They plan to develop the potato as a manufacturing platform for dozens (eventually hundreds) of ingredients. Turning the humble potato into one of the worlds most advanced manufacturing facilities. 🏭

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