🚀 Are You Pulling on All Three Biomanufacturing Optimisation Levers?

Are you fully leveraging cell biology to maximise efficiency and minimise COGS?

As more and more biomanufacturing companies seek to bring their products to market, pulling on all three optimisation levers—cell line development, media formulation, and bioprocess optimization—is critical for success.

When I entered the biomanufacturing space, I quickly learned that success depends on mastering these three levers. Like gears in a machine, each one needs to work in sync to drive optimal performance (ultimately defined as maximal yield for minimal cost).

Traditionally, you’d start with the right cell line, develop a suitable media, and then optimize the bioprocess for maximum yield. This sequential approach might have sufficed in a simpler era, where uniform cell lines and off-the-shelf media formulations could meet demands with decent yields, especially in the realm of stirred tank bioreactors.

But we’re now in an era of precision and customization. 🌐

With real-time insights from omics studies and in-line metabolite analyzers, we can analyze cell, media and bioprocess interactions in completely new ways. SaaS solutions that integrate these massive dataset are rapidly becoming the preferred option to an in-house data-science team. Add single-cell sorting technologies into the mix, and you’re dealing with an exciting—but complex—landscape of cell line heterogeneity and tailored environments.

The challenge? Getting all three levers—cell line, media, and bioprocess—working together in perfect sync.

To help biomanufacturing companies master this, I’ve created three (free) databases with insights on B2B companies specializing in cell line development, media formulation, and bioprocess optimisation. If you haven’t already, check them out (see here) and let me know what you think. 🚀