Innovating Bioprocess Design: A New Database Resource

Over the last couple of months, I've had the opportunity to speak with many founders and leaders in the biomanufacturing space. It's so exciting to see the level of innovation happening here! One area, in particular, gaining significant momentum is novel bioprocess design. 🌟

The trusty stirred tank design has been a staple in biopharma since its use for the mass production of penicillin during WWII. Since its humble beginnings, we've seen innovations across mixing and aeration, the incorporation of computational fluid dynamics, increased use of single-use systems, automated monitoring and process analytical technology, and increased cell density using perfusion and feeding strategies (to name just a few!). 🧬

With the transition to Industry 4.0 well underway, we're seeing an explosion of new bioreactor and bioprocess designs. From digital twin modeling, machine learning, and AI to hardware modifications, robotics, and automation, and new in-line monitoring and process control options. It is an incredible time to use biology to build new products in pharma, food, textiles, cosmetics, and specialty chemicals. 🧪🤖

In a 2020 McKinsey report, it was estimated that up to "60% of the physical inputs to the global economy could, in principle, be produced biologically." To achieve this, we need continuous and iterative innovations across the biomanufacturing value chain. 🌍

Given my strong personal interest in this space, I have started tracking as many companies as I can who are building innovative hardware or software solutions in the biomanufacturing space. If you are using biology to create incredible products, check out this brand-new bioprocessing database on my website now (see here), and keep an eye out for similar resources that I will share for cell line and media development. 📊